ASE-9720

iPSC-Derived Human T Cell Kit (African-American, Male Line)
iPSC-Derived T cell Kit (from AA) CD4+ CD8+

Applied StemCell has developed an efficient integration-free, small molecule-based method to differentiate high-quality T cells from human iPSCs. The differentiated T cells recapitulate the phenotype and functional parameters of primary and in vivo T cells. We provide T cells differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from the fibroblasts of an African-American male donor. These cells express T cell biomarkers, CD4+ and CD8+ (Figure 1). To harness the full potential of our T cells, we also provide optimized T Cell Basal Media (ASE9720MM) and T Cell Supplement (ASE-9720MM-A) that support robust maintenance and functionality of the T cells in culture. These iPSC-differentiated T cells can be used as control lines to compare phenotype and functionality of patient-derived, genome edited iPSC-derived T cells for drug screening applications. These T cells can also be used as effector cells for cytotoxicity assays.