| Table Header | Table Header |
|---|---|
Catalog Number | ASKI-190024 |
Model Name | Krt14-CreERT2 |
Strain Name | C57BL/6-Krt14em2(CreERT2-Wpre-polyA)/Asc |
GENE Synonyms | Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14 |
Human Orthologs | KRT14 |
Ensembl ID | ENSMUSG00000045545 |
MGI ID | 96688 |
NCBI ID | 16664 |
Background | C57BL/6 |
Coat Color | Black |
Model Type | Knock-in |
Research Application | Cre recombinase tool |
Model Color | Black |
A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene via CRISPR/Cas mediated recombination.
Figure 1: CreERT2-mediated recombination in Skin, Tongue & Esophagus of Krt14 CreERT2+/-; R26 tdTomato+/- mice.
A. Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen
B. Krt14-CreERT2+/-; Rosa26 tdTomato+/-
C. Rosa26 tdTomato+/-
Figure 2: Confocal images showing expression of tdTomato in Skin, Tongue & Esophagus of Krt14 CreERT2+/-; R26 tdTomato +/- mice.
A. Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen
B. Krt14-CreERT2+/-; Rosa26 tdTomato+/-
C. Rosa26 tdTomato+/-
Fill out the contact form below and a team member will be in touch within one business day.
