Slc17a6-CreERT2

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SKU ASKI-190011 Category Tag

Description

This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Validation Data

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Figure 1: Expression Pattern of Tomato in Slc17a6-CreERT2 +/-; R26- tdTomato+/- mice.

CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-; R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.Â