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NT5E

Name: NT5E
SKU: ASHU-200009
Availability: OutOfStock

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SKU: ASHU-200009

Category: Uncategorized

Expression of CD73 in the peripheral T cells collected from humanized CD73 mice were detected by FACS

Figure 1. The results showed that the expression of human CD73 can be detected in the peripheral T cells of humanized CD73 mice as same as in Hu-PBMC.

In vivo Validation of Anti-tumor Efficacy in a MC38 Tumor-bearing Model of Humanized CD73 Mice

Figure 2. In vivo validation of anti-tumor efficacy in a MC38 tumor-bearing model of humanized CD73 mice. Homozygous humanized CD73 mice were inoculated with MC38 colon cancer cells (expressing human CD73 rather than murine CD73). Mice were grouped when the tumor size was approximately 100 mm3 (n=6). Three human CD73 antibodies differently inhibited tumor growth, confirming that the CD73-HU mouse model is a powerful tool for in vivo CD73 antibody pharmacological efficacy study. A. Tumor average volume ± SEM, B. Mice average weight ± SEM.

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NT5E

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Expression of CD73 in the peripheral T cells collected from humanized CD73 mice were detected by FACS

In vivo Validation of Anti-tumor Efficacy in a MC38 Tumor-bearing Model of Humanized CD73 Mice

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NT5E

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Expression of CD73 in the peripheral T cells collected from humanized CD73 mice were detected by FACS

In vivo Validation of Anti-tumor Efficacy in a MC38 Tumor-bearing Model of Humanized CD73 Mice

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4-1BB (2)

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MTA Agreement

Material Transfer Agreement

TERMS AND CONDITIONS

Definitions

Scope of Use

Warranty; Warranty Disclaimer

Limitation of Liability