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PD-1 & SEMA4D

PD-1 & SEMA4D

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SKU ASHU-190033 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-190033
Model Name
PD-1 & SEMA4D
Strain Name
C57BL/6J – Pdcd1em1(hPDCD1) Sema4dem1(hSEMA4D)/Asc
GENE Synonyms
Ly101;CD100, Semaj, Semcl2, coll-4, Semacl2
Human Orthologs
PDCD1;SEMA4D
Ensembl ID
ENSMUSG00000026285;ENSMUSG00000021451
MGI ID
104879;109244
NCBI ID
18566;20354
Background
C57BL/6J
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy
Model Color
Black
This PD-1 and SEMA4D double Knock-in strain is established by crossing PD-1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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