Quality GMP-Grade iPSC and Knockin-Ready TARGATT™ iPSC
To jump start iPSC derived therapeutic cell product development; achieve reliable and efficient genome integration with our innovative solutions
GMP iPSC
Our high-quality GMP-grade iPSCs (ASE-9280) were reprogrammed from CD34+ male cord blood using an episomal reprogramming method and have proven gene editing and differentiation capabilities. The ready-to-use ASE-9280 GMP line and matching research-grade iPSCs (ASE-9250) are available for purchase. Expedite your project timelines by placing your order today!
- Source cell type: CD34+ Cord Blood, healthy male
- Reprogramming method: Episomal
- Master cell bank or working cell bank available
- Seed cell bank has Drug master file with US FDA
- Matching Research iPSC Line (ASE-9250) is Available
- Proven to be genomic stable (karyotype normal) and transgene expression stable post gene editing and differentiation
- No additional passthrough cost
- Partner with CIRM (California Institute of Regenerative Medicine) in supplying GMP grade iPSC lines
cGMP-Grade TARGATT™ iPSC (Gene Knock-in Ready)
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Case Studies
iPSC Characterization: Direct Differentiation to Three Germ Layers
Figure 1: Direct differentiation of ASE-9280 GMP Grade iPSCs to three germ layers. Staining for lineage-specific biomarkers of three germ layers after direct differentiation of the GMP hiPSC line, ASE-9280. The ASE-9280 GMP hiPSC line was differentiated to specific lineages of the germ layers using well-established and optimized protocols. Immunostaining for biomarkers of each lineage was performed. Cells were also co-stained with nuclear marker, DAPI (blue). Biomarkers: Ectoderm (EC) marker: Pax6 (green) and Tuj1 (red); Mesoderm (ME) marker: Brachyury (red) and GATA-4 (green); Endoderm (EN) marker: Fox2A (red) and Sox-17 (green).
iPSC Characterization: ASC’s cGMP iPSC Differentiate to Various Cell Types
ASC’s cGMP iPSC Differentiate to Islet Organoids
Bright-field image of ASE-9280 iPSC-derived pancreatic organoids
Fluorescent confocal image of ASE-9280 iPSC derived pancreatic organoids (insulin, NKX6.1, and DAPI)
Data provided by EssentiaASC’s cGMP iPSC Differentiate to Kidney Organoids
ASC’s cGMP iPSC Differentiate to Beating Cardiomyocytes
Click below to watch cGMP iPSC Differentiate to Beating Cardiomyocytes
Support Materials