The endogenous mouse Il2rb gene was replaced by human IL2RB gene.

Validation Data

landingpage-ashu-2000055-IL2RB-hu-icpmouse-1

Figure 1. Analysis of IL2RB gene expression in the liver by RT-PCR.

Mouse Il2rb mRNA was detectable by P1/2 (511bp), human IL2RB mRNA was detectable by P1/3(513bp)

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human IL2RB and mouse Il2rb in the liver.

Size

Mouse

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