Validation Data
Figure1. Human CD20 expression on B cells is confirmed by FACS analysis in the heterozygous humanized CD20 mice. The heterozygous KI animal expresses both human and murine CD20 on CD19+Â B cells.
Figure 2. Human CD20 expression on CD45+Â cells is confirmed by FACS analysis in WT, heterozygous, and homozygous humanized CD20 mice. The WT animal expresses mouse CD20 on CD45+Â cells, and the homozygous KI expresses human CD20, while the heterozygous KI expresses both human and murine CD20.
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