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Cd8a-IRES-Luc-2A-EGFP

Name: Cd8a-IRES-Luc-2A-EGFP
SKU: ASKI-18030
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SKU: ASKI-18030

A V5-IRES-luci-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled knock-in model with V5, luciferase and EGFP fluorescent protein.

Vallidation Data

Figure 1.Â In the absence of any stimulation, the in vivo imaging system detected that Cd8a^{V5-IRES-luci-2A-EGFP/+} mice showed significant fluorescence.Â

landingpage-aski-18030-Cd8a-IRES-Luc-2A-EGFP-ki-mouse-2

Figure 2.Â Â In vivoÂ imaging validation of MC38 tumors in Cd8a^{V5-IRES-luci-2A-EGFP/+}Â reporter mice treated or not with a PD-1 mAb. After 1 day of stimulation with PD1 antibody, the fluorescence was significantly enhanced.

landingpage-ashki-18030-Cd8a-IRES-Luc-2A-EGFP-ki-mouse-3

Figure 3.Â EGFP expression analysis inÂ PBMC of Cd8a^{V5-IRES-luci-2A-EGFP/+}Â mice by flow cytometry.

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Cd8a-IRES-Luc-2A-EGFP

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Vallidation Data

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Cd8a-IRES-Luc-2A-EGFP

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Vallidation Data

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MTA Agreement

Material Transfer Agreement

TERMS AND CONDITIONS

Definitions

Scope of Use

Warranty; Warranty Disclaimer

Limitation of Liability