| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASKI-18017 |
|
Model Name |
Cd2-2A-CreERT2 |
|
Strain Name |
C57BL/6J-Cd2em1(2A-CreERT2-WPRE-pA)/Asc |
|
GENE Synonyms |
Ly37, LFA-2, Ly-37 |
|
Human Orthologs |
CD2 |
|
Ensembl ID |
ENSMUSG00000027863 |
|
MGI ID |
88320 |
|
NCBI ID |
12481 |
|
Background |
C57BL/6J |
|
Coat Color |
Black |
|
Mutation Type |
Knock-in |
|
Model Type |
Knock-in |
|
Research Application |
Immunotherapy |
|
Model Color |
Black |
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted before the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
Figure 1. The result shows that expression pattern of RFP in T cells of Cd2-(2A-CreERT2-WPRE-pA); RFP.
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