| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-210007 |
|
Model Name |
FAS |
|
Strain Name |
C57BL/6J-Fasem1(hTNFRSF6)/Asc |
|
GENE Synonyms |
AP, TNF, lpr, APO1, APT1, CD95, Tnfr, TNFR6, Tnfrsf6, AI196731 |
|
Human Orthologs |
FAS |
|
Ensembl ID |
ENSMUSG00000024778 |
|
MGI ID |
95484 |
|
NCBI ID |
14102 |
|
Background |
C57BL/6J |
|
Coat Color |
Black |
|
Model Type |
Humanized |
|
Research Application |
Immunotherapy, drug screening |
|
Model Color |
Black |
The endogenous mice Fas gene was replaced by human FAS gene.
Figure 1. Detection of FAS expression in thymus and lung by RT-PCR.
Wild type: only one band at 286 bp with primers F1/R1 (mFas);Heterozygous: one band at 286 bp with primers F1/R1 (mFas) and one band at 304 bp with primers F2/R2 (hFAS); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
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