The endogenous mice Gcgr gene was replaced by human GCGR gene.

Validation Data

landingpage-ashu-215004-gcgr-hu-icpmouse-1

Figure 1. Detection of GCGR expression in liver by RT-PCR. 

Wild type: only one band at 261 bp with primers F1/R1 (mGcgr); Heterozygous: one band at 261 bp with primers F1/R1 (mGcgr) and one band at 223 bp with primers F2/R2 (hGCGR); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

landingpage-ashu-215004-gcgr-hu-icpmouse-2

Figure 2. Detection of human GCGR expression in liver in hGCGR knockin mice by IHC. 

Liver were collected from wild-type mice (+/+) and homozygous hGCGR mice (HO/HO), and analyzed by IHC with anti-human GCGR antibody. 

Size

Mouse

Reviews

There are no reviews yet.

Be the first to review “GCGR”

Your email address will not be published. Required fields are marked *