| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-204987 |
|
Model Name |
HLA-A11 |
|
Strain Name |
C57BL/6J-H2-K1em1(hHLA-A11)/Asc |
|
GENE Synonyms |
K-f, H-2K, H2-K, H2-D1, H2-K_p, H-2K(d) |
|
Human Orthologs |
HLA-A, HLA-E, HLA-F |
|
Ensembl ID |
ENSMUSG00000061232 |
|
MGI ID |
95904 |
|
NCBI ID |
14972 |
|
Background |
C57BL/6J |
|
Coat Color |
Black |
|
Model Type |
Humanized |
|
Research Application |
Tumor research, drug screening |
|
Model Color |
Black |
The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.
Figure 1. Detection of HLA-A11 expression in liver and spleen by RT-PCR.
Wild type: only one band at 369 bp with primers F1/R1 (mH2-k1); Heterozygous: one band at 369 bp with primers F1/R1 (mH2-k1) and one band at 215 bp with primers F2/R2 (hHLA-A11); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
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