Humanized Strategy
Strategy for Generating Humanized PD-L1 (ASHU-00062) Mouse Model
Strategy for Generating Humanized LAG3 (ASHU-00049) Mouse Model
Validation Data
Figure 1. Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. The mPDL1+ and mLAG3+ cells were detectable in wild type (WT) C57BL/6 mice, while the hPDL1+ and hLAG3+ cells were detectable in the homozygous hPD1/hLAG3 mice.
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