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Aplnr-DreERT2

Aplnr-DreERT2

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SKU ASKI-00132 Categories , ,

Strain Information

Table Header Table Header
Catalog Number
ASKI-00132
Model Name
Aplnr-DreERT2
Strain Name
C57BL/6J-Aplnrem1(2A-DreERT2)Asc
GENE Synonyms
Agtrl1, apelin receptor, APJ, msr/apj
Human Orthologs
APLNR
Ensembl ID
ENSMUSG00000044338
MGI ID
1346086
NCBI ID
23796
Background
C57BL/6J
Coat Color
Black
Model Type
Knock-in
Research Application
Immunotherapy
A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.
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