C57BL/6J-Drd1em1(2A-CreERT2-WPRE-pA)Asc

SKU ASKI-18016 Categories Cre Mouse Models, Mouse Models, Other Gene Edited Mouse Models (KO, CKO), Products

Strain Information

Table Header	Table Header
Catalog Number	ASKI-18016
Model Name	Drd1-(2A-CreERT2-WPRE-pA)
Strain Name	ASKI-18016
GENE Synonyms	Drd-1; Drd1a; Gpcr15; C030036C15Rik
Human Orthologs	DRD1
Ensembl ID	ENSMUSG00000021478
MGI ID	13488
NCBI ID	1812
Background	C57BL/6J
Coat Color	Black
Mutation Type	Knock-in
Model Type	C57BL/6J-Drd1em1(2A-CreERT2-WPRE-pA)Smoc
Research Application	Immunotherapy

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

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