C57BL/6J-Tie1em1(2A-Cre)Asc

SKU ASKI-18023 Categories Cre Mouse Models, Mouse Models, Other Gene Edited Mouse Models (KO, CKO), Products

Strain Information

Table Header	Table Header
Catalog Number	ASKI-18023
Model Name	Tie1-(2A-Cre)
Strain Name	ASKI-18023
GENE Synonyms	TIE; tie-1; D430008P04Rik
Human Orthologs	TIE1
Ensembl ID	ENSMUSG00000033191
MGI ID	99906
NCBI ID	21846
Background	C57BL/6J
Coat Color	Black
Mutation Type	Knock-in
Model Type	C57BL/6J-Tie1em1(2A-Cre)Smoc
Research Application	Immunotherapy

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

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