C57BL/6J-Zbtb46em1(2A-CreERT2-WPRE-pA)Asc

Strain Information

Table Header Table Header
Catalog Number
ASKI-18021
Model Name
Zbtb46-(2A-CreERT2-WPRE-pA)
Strain Name
ASKI-18021
GENE Synonyms
BZEL; Btbd4; 2610019F01Rik; 4933406L05Rik
Human Orthologs
ZBTB46
Ensembl ID
ENSMUSG00000027583
MGI ID
1919397
NCBI ID
72147
Background
C57BL/6J
Coat Color
Black
Mutation Type
Knock-in
Model Type
C57BL/6J-Zbtb46em1(2A-CreERT2-WPRE-pA)Smoc
Research Application
Immunotherapy
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Zbtb46 gene via homologous recombination to establish a tamoxifen inducible Zbtb46-CreERT2 tool stain. This strain can be used to knockout target gene in Zbtb46+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

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