CCR8 (2) & CTLA-4

Strain Information

Table Header Table Header
Catalog Number
ASHU-220074
Model Name
CCR8 (2) & CTLA-4
Strain Name
C57BL/6J-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)/Asc
GENE Synonyms
C-C, CCR-8, CKR-8, mCCR8, Cmkbr8, CC-CKR-8, C-C CKR-8; Cd152, Ly-56, Ctla-4
Human Orthologs
CCR8; CTLA4
Ensembl ID
ENSMUSG00000042262; ENSMUSG00000026011,
MGI ID
1201402; 88556
NCBI ID
12776; 12477
Background
C57BL/6J
Coat Color
Black
Model Type
Humanized
Model Color
Black

hCTLA4 (ASHU-00014) mice were crossed with hCCR8 (2) (ASHU-2000054) mice to generate hCCR8(2)/hCTLA4 mice.

Validation Data

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Figure 1. Statistics of hCCR8 and hCTLA-4 expression in hCCR8 (2)/hCTLA-4 dKI mice.

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Figure 2. Detection of hCCR8 and CTLA-4 expression on T cells in Tumor in hCCR8 (2)/hCTLA-4 dKI mice.

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Figure 3. Detection of hCCR8 and hCTLA-4 expression on T cells in Spleen in hCCR8 (2)/hCTLA-4 dKI mice.

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