CD2

The endogenous mice Cd2 gene was replaced by human CD2 gene.

Validation Data

Figure1. Detection of CD2 expression in thymus and spleen by RT-PCR. Wild type: only one band at 432 bp with primers F1/R1 (mCd2); Heterozygous: one band at 432 bp with primers F1/R1 (mCd2) and one band at 228 bp with primers F2/R2 (hCD2); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

Figure 2. Detection of hCD2 expression on Jurkat cell line.

Figure 3. Detection of hCD2 expression on T cells in Blood in hCD2 KI mice.

Figure 4. Detection of hCD2 expression on T cells in Spleen in hCD2 KI mice.

Figure 5. Detection of hCD2 expression on B cells in hCD2 KI mice.

Figure 6. Detection of hCD2 expression on NK cells in hCD2 KI mice.