CD28

Strain Information

Table Header Table Header
Catalog Number
ASHU-190011
Model Name
CD28
Strain Name
C57BL/6-Cd28em2(hCD28)/Asc
Human Orthologs
CD28
Ensembl ID
ENSMUSG00000026012
MGI ID
88327
NCBI ID
12487
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy
Model Color
Black

Humanized Strategy

landingpage-ashu-190011-cd28-hu-icpmouse-1

Validation Data

landingpage-ashu-190011-cd28-hu-icpmouse-4

Figure 1. Expression characterization of hCD28 on T cells in blood in hCD28 KI mice

landingpage-ashu-190011-cd28-hu-icpmouse-5

Figure 2. Expression characterization of hCD28 on T cells in spleen in hCD28 KI mice

landingpage-ashu-190011-cd28-hu-icpmouse-6

Figure 3. Expression characterization of hCD28 on T cells in thymus in hCD28 KI mice

landingpage-ashu-190011-cd28-hu-icpmouse-7

Figure 4. In vivo efficacy study in CD28 humanized mice grafted with MC38-hPDL1 tumor model

Ready to learn more?

Fill out the contact form below and a team member will be in touch within one business day.