CD3E

SKU ASHU-00114 Categories Immune Checkpoint Mouse Models, Mouse Models, Products

Strain Information

Table Header	Table Header
Catalog Number	ASHU-00114
Model Name	CD3E
Strain Name	C57BL/6-Cd3e^{em1(hCD3E)/Asc}
GENE Synonyms	CD3, T3e, AI504783, CD3epsilon
Human Orthologs	CD3E
Ensembl ID	ENSMUSG00000032093
MGI ID	88332
NCBI ID	12501
Background	C57BL/6
Coat Color	Black
Mutation Type	Humanized
Model Type	Humanized
Research Application	Immunotherapy, cancer research, drug screening
Model Color	Black

Humanized Gene Knock-in Strategy

Validation Data

Figure 1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS.

Figure 2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

Figure 3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.

Figure 4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.

Ready to learn more?

Fill out the contact form below and a team member will be in touch within one business day.

Contact form