Strain Information

Table Header Table Header
Catalog Number
ASHU-00045
Model Name
CD86
Strain Name
C57BL/6-Cd86em1(hCD86)/Asc
GENE Synonyms
B7, B7-2, B7.2, B70, CLS1, Cd28l2, ETC-1, Ly-58, Ly58, MB7, MB7-2
Human Orthologs
CD86
Ensembl ID
ENSMUSG00000022901
MGI ID
101773
NCBI ID
12524
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy, cancer research, drug screening
Model Color
Black

The endogenous mouse Cd86 gene was replaced by human CD86 gene via CRISPR/Cas mediated recombination.

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