| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-210032 |
|
Model Name |
EPCAM |
|
Strain Name |
C57BL/6-Epcamtm1(hEPCAM)/Asc |
|
GENE Synonyms |
EGP, Ly74, gp40, CD326, EGP-2, TROP1, Egp314, Ep-CAM, EpCAM1, Tacsd1, GA733-2, Tacstd1 |
|
Human Orthologs |
EPCAM |
|
Ensembl ID |
ENSMUSG00000045394 |
|
MGI ID |
106653 |
|
NCBI ID |
17075 |
|
Background |
C57BL/6 |
|
Coat Color |
Black |
|
Mutation Type |
Humanized |
|
Model Type |
Humanized |
|
Research Application |
Immunotherapy, drug screening |
|
Model Color |
Black |
Figure1. Analysis of mouse EPCAM and human EPCAM protein expression in the large intestine by IHC.
Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse expresses human EPCAM in the crypts significantly.
Figure 2. Analysis of mouse EPCAM and human EPCAM protein expression in the small intestine by IHC.
Both the EPCAM humanized heterozygous mouse and wild type express mouse EPCAM in the mucosal epithelial membranes, and the humanized heterozygous mouse expresses human EPCAM in the crypts significantly.
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