FCGR2B

SKU ASHU-2000010 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-2000010
Model Name
FCGR2B-HU
Strain Name
C57BL/6-Fcgr2bem3(FCGR2B)Asc
GENE Synonyms
AI528646, CD32, F630109E10Rik, Fc[g]RII, FcgRII, Fcgr2, Fcgr2a, Fcr-2, Fcr-3, Ly-17, Ly-m20, LyM-1, Lym-1, fcRII
Human Orthologs
FCGR2B
Ensembl ID
ENSMUSG00000026656
MGI ID
95499
NCBI ID
14130
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanization
Model Type
Humanization
Research Application
Immunotherapy, cancer research, drug screening
Model Color
Black
The endogenous mouse Fcgr2b gene was replaced by human FCGR2B gene.

Validation Data

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Figure 1. The expression of human FCGR2B(CD32) in the peripheral blood cells derived from heterozygous humanized mice was confirmed by FACS. 

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