| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-00109 |
|
Model Name |
FCRN |
|
Strain Name |
C57BL/6J – Gt(ROSA)26Sorem1(CAG – hFcRn)Fcgrtem1/Asc |
|
GENE Synonyms |
FcRn |
|
Human Orthologs |
FCGRT |
|
Ensembl ID |
ENSMUSG00000003420 |
|
MGI ID |
103017 |
|
NCBI ID |
14132 |
|
Background |
C57BL/6 |
|
Coat Color |
Black |
|
Mutation Type |
Humanized |
|
Model Type |
Humanized |
|
Research Application |
Cancer research, Immunotherapy, drug screening |
|
Model Color |
Black |
Figure 1. The expression of mouse FCGRT and human FCGRT in liver was confirmed by western blotting.
Figure 2. PK validation of human antibody (ustekinumab and briakinumab) in FCGRT humanized Mice.
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