| Table Header | Table Header |
|---|---|
Catalog Number | ASHU-215002 |
Model Name | GDF15 |
Strain Name | C57BL/6J-Gdf15em(hGDF15)/Asc |
GENE Synonyms | SBF, MIC-1, NAG-1 |
Human Orthologs | GDF15 |
Ensembl ID | ENSMUSG00000038508 |
MGI ID | 1346047 |
NCBI ID | 23886 |
Background | C57BL/6J |
Coat Color | Black |
Model Type | Humanized |
Model Color | Black |
The endogenous mice Gdf15 gene was replaced by human GDF15 gene.
Figure 1. Detection of GDF15 expression in intestine and colon and liver by RT-PCR.
Wild type: only one band at 314 bp with primers F1/R1 (mGdf15); Homozygous: only one band at 160 bp with primers F2/R2 (hGDF15); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Figure 2. Detection of hGDF15 expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
Figure 3. Detection of mGDF15 expression in plasma by ELISA.
Abbr. HO, homozygous; HE, heterozygous; WT, wild type.
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