Il1a-(Luc-EGFP)

SKU ASKI-00009 Category Other Gene Edited Mouse Models (KO, CKO)

Strain Information

Table Header	Table Header
Catalog Number	ASKI-00009
Model Name	Il1a-(Luc-EGFP)
Strain Name	C57BL/6J-Il1a^{em1(Luc-eGFP)Asc}
GENE Synonyms	Il-1a
Human Orthologs	IL1A
Ensembl ID	ENSMUSG00000027399
MGI ID	96542
NCBI ID	16175
Background	C57BL/6J
Coat Color	Black
Model Type	Knock-in
Research Application	Immunotherapy

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon via CRISPR/Cas mediated recombination. According to this strategy, the endogenous Il1a expression is supposed to be eliminated and the intrisic promoter drives the expression of reporter genes, which reflexs the activity of Il1a.

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