Il1b-(Luc-EGFP)

SKU ASKI-00010 Category Other Gene Edited Mouse Models (KO, CKO)

Strain Information

Table Header	Table Header
Catalog Number	ASKI-00010
Model Name	Il1b-(Luc-EGFP)
Strain Name	C57BL/6J-Il1b^{em1(Luc-eGFP)Asc}
GENE Synonyms	Il-1b, IL-1beta
Human Orthologs	IL1B
Ensembl ID	ENSMUSG00000027398
MGI ID	96543
NCBI ID	16176
Background	C57BL/6J
Coat Color	Black
Model Type	Knock-in
Research Application	Immunotherapy

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene via CRISPR/Cas mediated recombination. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

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