| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-200255 |
|
Model Name |
IL21 |
|
Strain Name |
C57BL/6J-Il21tm1(hIL21)/Asc |
|
GENE Synonyms |
IL-21 |
|
Human Orthologs |
IL21 |
|
Ensembl ID |
ENSMUSG00000027718 |
|
MGI ID |
1890474 |
|
NCBI ID |
60505 |
|
Background |
C57BL/6J |
|
Coat Color |
Black |
|
Model Type |
Humanized |
|
Model Color |
Black |
The endogenous mouse Il21 gene was replaced by human IL21 gene.
Figure 1. Detection of IL21 expression in splenocyte by RT-PCR.
Wild type: only one band at 272 bp with primers F1/R1(mIl21); Homozygous: only one band at 304 bp with primers F2/R2(hIL21); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.
Figure 2. Detection of hIL21 expression in splenocyte culture supernatants by ELISA (n=3).
Abbr. HO, homozygous; HE, heterozygous; WT, wild type. Note. hIL21 and C57BL/6 mice were stimulated with ConA in vitro.
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