IL23A

SKU ASHU-18030 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-18030
Model Name
IL23A
Strain Name
C57BL/6-Il23aem3(hIL23A)/Asc
GENE Synonyms
p19, IL-23
Human Orthologs
IL23A
Ensembl ID
ENSMUSG00000025383
MGI ID
1932410
NCBI ID
83430
Background
C57BL/6
Coat Color
Black
Model Type
Humanized
Research Application
Immunotherapy, cancer research, drug screening
Model Color
Black

The endogenous mouse Il23a gene was replaced by humanIL23A gene.

Validation Data

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Figure1. Detection of hIL-23A RNA expression by RT-PCR (Data in partnership with collaborators)

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Figure 2. In vivo efficacy evaluation of anti-IL-23 in imiquimod (IMQ)-induced psoriasis model in hIL23A mice (Data in partnership with collaborators)

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