IL2RG & IL2RB

SKU ASHU-210354 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-210354
Model Name
IL2RG & IL2RB
Strain Name
C57BL/6-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)/Asc
GENE Synonyms
p70, CD122, IL15Rbeta, Il-2Rbeta, IL-15Rbeta, Il-2/15Rbeta; gc, p64, [g]c, CD132, gamma(c)
Human Orthologs
IL2RB; IL2RG
Ensembl ID
ENSMUSG00000068227; ENSMUSG00000031304
MGI ID
96550; 96551
NCBI ID
16185; 16186
Background
C57BL/6
Coat Color
Black
Model Type
Humanized
Research Application
Immunotherapy, drug screening
Model Color
Black

hIL2RG (ASHU-200007) was crossed with hIL2RB (ASHU-2000055) to generate hIL2RG/hIL2RB mice.

Validation Data

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Figure1. Detection of hCD122 expression in hIL2RG/hIL2RB dKI mice.

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Figure 2. Detection of hCD132 expression in hIL2RG/hIL2RB dKI mice.

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Figure 3. Detection of immune phenotyping in peripheral blood and spleen in hIL2RG/hIL2RB dKI mice.

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