$1,650.00
We use our efficient, integration-free, small-molecule-based method to differentiate high-quality dopaminergic (DOPA) neurons from human iPSCs. The differentiated DOPA neurons recapitulate the phenotype and functional parameters of primary and in vivo dopaminergic neurons.
We provide dopaminergic neurons differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from the fibroblasts of an African American male donor. These high-purity (>70%) cells express high levels of the dopaminergic neuron biomarker TH.
These iPSC-differentiated DOPA neurons can be used as control lines to compare the phenotype and functionality of patient-derived, genome-edited iPSC-derived DOPA neurons for drug screening applications. The dopaminergic neurons can also be used for neurotoxicity assays.
| Table Header | Table Header |
|---|---|
|
Age |
Neonate |
|
Gender |
Male |
|
Ethnicity |
African American |
|
Tissue source |
Dermal fibroblasts |
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Reprogramming method |
Episomal |
|
Culture conditions |
Feeder-free |
