PD-1 & CD3E

SKU ASHU-18021 Category Immune Checkpoint Mouse Models

Strain Information

Table Header	Table Header
Catalog Number	ASHU-18021
Model Name	PD-1 & CD3E
Strain Name	C57BL/6-Pdcd1^{em1(hPDCD1) Cd3eem1(hCD3E)/Asc}
GENE Synonyms	Ly101, CD3, T3e, AI504783, CD3epsilon
Human Orthologs	PDCD1, CD3E
Ensembl ID	ENSMUSG00000026285, ENSMUSG00000032093
MGI ID	104879, 88332
NCBI ID	18566, 12501
Background	C57BL/6
Coat Color	Black
Mutation Type	Humanized
Model Type	Humanized
Research Application	Immunotherapy, cancer research, drug screening
Model Color	Black

This PD-1 and CD3e double knockin strain is established by crossing PD-1-HU and CD3e-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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