| Table Header | Table Header |
|---|---|
Catalog Number | ASHU-190060 |
Model Name | PD-1 & PD-L1 & PDCD1LG2 |
Strain Name | C57BL/6 – Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Asc |
GENE Synonyms | PD-1, Pdc1, Ly101, B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, Btdc, B7-DC, PD-L2, 730015O22Rik |
Human Orthologs | PDCD1, CD274, PDCD1LG2 |
Ensembl ID | ENSMUSG00000026285, ENSMUSG00000016496, ENSMUSG00000016498 |
MGI ID | 104879, 1926446, 1930125 |
NCBI ID | 18566, 60533, 58205 |
Background | C57BL/6 |
Coat Color | Black |
Mutation Type | Humanized |
Model Type | Humanized |
Research Application | Immunotherapy, cancer research, drug screening |
Model Color | Black |
The endogenous mouse Pd-1/Pd-l1/Pdcd1lg2 gene was replaced by human PD-1/PD-L1/PDCD1LG2 gene via CRISPR/Cas mediated recombination.
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