PD-1 & TLR9

SKU ASHU-190023 Category Immune Checkpoint Mouse Models

Strain Information

Table Header	Table Header
Catalog Number	ASHU-190023
Model Name	PD-1 & TLR9
Strain Name	C57BL/6J – Pdcd1^{em1(hPDCD1) Tlr9 tm1(hTLR9)/Asc}
GENE Synonyms	Ly101
Human Orthologs	PDCD1; TLR9
Ensembl ID	ENSMUSG00000026285; ENSMUSG00000045322
MGI ID	104879; 1932389
NCBI ID	18566; 81897
Background	C57BL/6J
Coat Color	Black
Mutation Type	Humanized
Model Type	Humanized
Research Application	Immunotherapy
Model Color	Black

This PD-1 and TLR9 double Knock-in strain is established by crossing PD-1-HU and TLR9-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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