PD-L1 & CD40

SKU ASHU-18024 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-18024
Model Name
PD-L1 & CD40
Strain Name
C57BL/6-Cd274em1(hPD – L1) Cd40em1(hCD40)/Asc
GENE Synonyms
B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
Human Orthologs
CD274, CD40
Ensembl ID
ENSMUSG00000016496, ENSMUSG00000017652
MGI ID
1926446, 88336
NCBI ID
60533, 21939
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy, cancer research, drug screening
Model Color
Black
This PD-L1 and CD40 double knockin strain is established by crossing PD-L1-HU and CD40-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.

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