| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASHU-190015 |
|
Model Name |
PD-L1 & GITR |
|
Strain Name |
C57BL/6J – Cd274em1(hPD – L1)Tnfrsf18em1(hTNFRSF18)/Asc |
|
GENE Synonyms |
B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik; AITR, Gitr |
|
Human Orthologs |
CD274; TNFRSF18 |
|
Ensembl ID |
ENSMUSG00000016496; ENSMUSG00000041954 |
|
MGI ID |
1926446; 894675 |
|
NCBI ID |
60533;21936 |
|
Background |
C57BL/6J |
|
Coat Color |
Black |
|
Mutation Type |
Humanized |
|
Model Type |
Humanized |
|
Research Application |
Immunotherapy |
|
Model Color |
Black |
This PD-L1 and GITR double Knock-in strain is established by crossing PD-L1-HU and GITR-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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