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PD-L1 & SEMA4D

PD-L1 & SEMA4D

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SKU ASHU-190034 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-190034
Model Name
PD-L1 & SEMA4D
Strain Name
C57BL/6J – Cd274em1(hPD – L1) Sema4dem1(hSEMA4D)/Asc
GENE Synonyms
B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik;CD100, Semaj, Semcl2, coll-4, Semacl2
Human Orthologs
CD274;SEMA4D
Ensembl ID
ENSMUSG00000016496;ENSMUSG00000021451
MGI ID
1926446;109244
NCBI ID
60533;20354
Background
C57BL/6J
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy
Model Color
Black
This PD-L1 and SEMA4D double Knock-in strain is established by crossing PD-L1-HU and SEMA4D-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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