PD-L1 & TIM3

SKU ASHU-190056 Category Immune Checkpoint Mouse Models

Strain Information

Table Header	Table Header
Catalog Number	ASHU-190056
Model Name	PD-L1 & TIM3
Strain Name	C57BL/6J – Cd274^{em1(hPD – L1)Havcr2em1(hHAVCR2)/Asc}
GENE Synonyms	B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik,Tim3, TIM-3, Timd3
Human Orthologs	CD274; HAVCR2
Ensembl ID	ENSMUSG00000016496;ENSMUSG00000020399
MGI ID	1926446;2159682
NCBI ID	60533; 171285
Background	C57BL/6
Coat Color	Black
Mutation Type	Humanized
Model Type	Humanized
Research Application	Immunotherapy
Model Color	Black

This PD-L1 and TIM3 double Knock-in strain is established by crossing PD-L1-HU and TIM3-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

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