R26-(C-MET)

SKU ASKI-18052 Category Other Gene Edited Mouse Models (KO, CKO)

Strain Information

Table Header	Table Header
Catalog Number	ASKI-18052
Model Name	R26-(C-MET)
Strain Name	C57BL/6J-Gt(ROSA)26Sor^{em1(CAG-LSL-c-MET-IRES-luciferase-2A-tdTomato)Asc}
Human Orthologs	C-MET
Background	C57BL/6J
Coat Color	Black
Model Type	Knock-in
Research Application	Immunotherapy

A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human cMET-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase so that human C-MET could be expressed after exposure to Cre recombinase.

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