R26-(CAG-LSL-HER2-luciferase-EGFP)

SKU ASKI-190008 Category

Strain Information

Table Header Table Header
Catalog Number
ASKI-190008
Model Name
R26-(CAG-LSL-HER2-luciferase-EGFP)
Strain Name
C57BL/6J-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-HER2-luciferase-EGFP)Asc
Ensembl ID
ENSMUSG00000086429
MGI ID
104735
NCBI ID
14910
Background
C57BL/6J
Coat Color
Black
Model Type
Knock-in
Research Application
Immunotherapy
A SA-2xpolyA-CAG-LSL-HER2-IRES-Luciferase-2A-EGFP-WPRE-polyA cassette was inserted at the Rosa26 locus using CRISPR gene editing technology. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the HER2 protein.

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