R26-(CAG-LSL-Itpr1-Flag-tdTomato)

SKU ASKI-18046 Category Other Gene Edited Mouse Models (KO, CKO)

Strain Information

Table Header	Table Header
Catalog Number	ASKI-18046
Model Name	R26-(CAG-LSL-Itpr1-Flag-tdTomato)
Strain Name	C57BL/6J-Gt(ROSA)26Sorem(CAG-LSL-Itpr1-3xFlag-IRES-tdTomato-wpre-polyA)Asc
GENE Synonyms	InsP3R type I, Ip3r, IP3R1, Itpr-1, opt, P400, Pcp1, Pcp-1, wblo
Human Orthologs	ITPR1
Ensembl ID	ENSMUSG00000030102
MGI ID	96623
NCBI ID	16438
Background	C57BL/6J
Coat Color	Black
Model Type	Knock-in
Research Application	Immunotherapy

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Itpr1-3xFlag-IRES-tdTomato expression cassette. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by CRISPR/Cas mediated homologous recombination.

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