R26-(EZH2)

Strain Information

Table Header Table Header
Catalog Number
ASKI-18053
Model Name
R26-(EZH2)
Strain Name
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Asc
Human Orthologs
EZH2
Background
C57BL/6J
Coat Color
Black
Model Type
Knock-in
Research Application
Immunotherapy
A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.

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