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R26-(NRF2)

R26-(NRF2)

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SKU ASKI-18050 Category

Strain Information

Table Header Table Header
Catalog Number
ASKI-18050
Model Name
R26-(NRF2)
Strain Name
C57BL/6J-Gt(ROSA)26Sorem1(CAG-LSL-NRF2-IRES-luciferase-2A-tdTomato)Asc
Human Orthologs
NRF2
Background
C57BL/6J
Coat Color
Black
Model Type
Knock-in
Research Application
Immunotherapy
A SA-2xpolyA-CAG-LSL-human NRF2-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase to express human NRF2 and a reporter gene in certain cells or tissues that expressing Cre recombinase.
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