SIRPA (2)

SKU ASHU-18015 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-18015
Model Name
SIRPA (2)
Strain Name
C57BL/6 – Sirpatm2(hSIRPA)/Asc
GENE Synonyms
Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480
Human Orthologs
SIRPA
Ensembl ID
ENSMUSG00000037902
MGI ID
108563
NCBI ID
19261
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy, drug screening
Model Color
Black

Humanized Gene Knock-in Strategy

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-1

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-2

Expression of hSIRPA Expression in PBMC of Heterozygous Mice Using FACS

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-3

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA-HU Mice

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-4

Efficacy of Anti-CD47 Treatment in a MC38 Syngeneic Tumor Model of SIRPA/CD47 Double Humanized Mice

Landingpage-ASHU-18015-SIRPA-HU-ICPMouse-5

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