| Table Header | Table Header |
|---|---|
|
Catalog Number |
ASKI-190011 |
|
Model Name |
Slc17a6-CreERT2 |
|
Strain Name |
C57BL/6-Slc17a6em2(CreERT2)/Asc |
|
GENE Synonyms |
DNPI, Vglut2, 2900073D12Rik |
|
Human Orthologs |
SLC17A6 |
|
Ensembl ID |
ENSMUSG00000030500 |
|
MGI ID |
2156052 |
|
NCBI ID |
140919 |
|
Background |
C57BL/6 |
|
Coat Color |
Black |
|
Mutation Type |
Knock-in |
|
Model Type |
Knock-in |
|
Research Application |
Tool mice |
|
Model Color |
Black |
This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.
Figure 1: Expression Pattern of Tomato in Slc17a6-CreERT2 +/-; R26- tdTomato+/- mice.
CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-; R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons.
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