TLR9 & OX40

SKU ASHU-190024 Category

Strain Information

Table Header Table Header
Catalog Number
ASHU-190024
Model Name
TLR9 & OX40
Strain Name
C57BL/6 – Tlr9 tm1(hTLR9) Tnfrsf4em3(hTNFRSF4)/Asc
GENE Synonyms
Ox40, ACT35, CD134, Ly-70, Txgp1, TXGP1L
Human Orthologs
TLR9, TNFRSF4
Ensembl ID
ENSMUSG00000045322, ENSMUSG00000029075
MGI ID
1932389, 104512
NCBI ID
81897, 22163
Background
C57BL/6
Coat Color
Black
Mutation Type
Humanized
Model Type
Humanized
Research Application
Immunotherapy
Model Color
Black
This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.

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