Trpv2-CKO

SKU ASCKO-00023 Category Other Gene Edited Mouse Models (KO, CKO)

Strain Information

Table Header	Table Header
Catalog Number	ASCKO-00023
Model Name	Trpv2-CKO
Strain Name	B6.129-Trpv2tm1(flox)Asc
GENE Synonyms	OTRPC2, Vrl1, VRL-1
Human Orthologs	TRPV2
Ensembl ID	ENSMUSG00000018507
MGI ID	1341836
NCBI ID	22368
Background	B6;129
Coat Color	Black
Model Type	Conditional knockout
Research Application	Immunotherapy

These Trpv2 gene flox mice can be used to abtain tissue specific knockout Trpv2 mice when cross with Cre transgenic mice. Mice homozygous for a conventional knock-out allele exhibit impaired macrophage migration, binding, and phagocytosis with increased susceptiblity and mortality following bacterial infection.

Ready to learn more?

Fill out the contact form below and a team member will be in touch within one business day.

Contact form