TARGATT™ iPSCs
Our TARGATT™ iPSC system provides a robust platform for cell line model creation and therapeutic cell product development with the ability to insert 20 kb+ of DNA and produce unlimited amounts of genetically uniform differentiated cells. Create cell lines that express large proteins or multiple genes in their native cell type to more faithfully capture physiological conditions.
TARGATT™ master iPSCs are pluripotent stem cells with a pre-engineered landing pad, attP site, in the H11 safe genomic locus ready for repeated, fast, and efficient gene knock-in by TARGATT™ integrase. The resulting gene edited iPSC can be differentiated to make unlimited, truly off-the-shelf cell products.
Why you should choose the TARGATT™, Master iPSC Line
Products and Services
Publications
TARGATT™ Master Cell Line
Transgenic Mouse Book Chapters
Description of the technology
Commentary, comparison with other transgenic methods
Tet inducible mice generated by TARGATT™
Advantage of Hipp11 (H11) locus
Applications for TARGATT™ technology